21 regressing without A & E? (4)

Times Cryptic #29446 | 25 Across | 2026-01-22
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I haven't cracked this one yet — but the brilliant team at Times for the Times have:

My last in, only falling when I realised the E needed to be detached. Since 21a is DEFEND, Thesaurus it to GUARD, remove  the A, and reverse.

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