What does the cryptic crossword clue "5 is negative with whichever case (5)" mean?

The definition is "5". The wordplay uses a container (one word inside another). NO (synonym="negative") in ANY (synonym="whichever") = ANNOY The answer is ANNOY.

5 is negative with whichever case (5)

Independent Cryptic #11795 | 24 Across | 2024-07-30 flower

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