What does the cryptic crossword clue "A hard request disrupted nerve centre (12)" mean?

The definition is "nerve centre". The wordplay uses an anagram. anagram of A + HARD + REQUEST = HEADQUARTERS; definition: "nerve centre" The answer is HEADQUARTERS.

A hard request disrupted nerve centre (12)

Daily Mail Cryptic #17451 | 29 Across | 2024-09-23 flower

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