What does the cryptic crossword clue "A pile's mixed up with vital pain relievers (11)" mean?

The wordplay uses an anagram. anagram of A + PILE'S + VITAL = PALLIATIVES The answer is PALLIATIVES.

A pile's mixed up with vital pain relievers (11)

Daily Mail Cryptic #17564 | 1 Across | 2025-02-27 flower