What does the cryptic crossword clue "Addicts run out of sympathisers (6)" mean?

This cryptic clue uses wordplay to arrive at the answer. Visit the page for progressive hints — definition, wordplay type, and a full step-by-step explanation.

Addicts run out of sympathisers (6)

Guardian Cryptic #29553 | 19 Down | 2024-11-29

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I haven't cracked this one yet — but the brilliant team at Fifteensquared have:

FRIENDS less R

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