What does the cryptic crossword clue "Charlie's best friend left where Americans live (5)" mean?

The definition is "Charlie’s best friend". The wordplay uses a charade (building blocks). L (synonym="left") + IN (synonym="left") + US (synonym="where Americans live") = LINUS The answer is LINUS.

Charlie's best friend left where Americans live (5)

Independent Cryptic #11851 | 5 Down | 2024-10-03 flower

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