What does the cryptic crossword clue "Crosophile initially took (consumed) an ace drug (9)" mean?

The definition is "drug". The wordplay uses a charade (building blocks). ME (synonym="the setter; Crosophile") + T (synonym="first letter of [initially] T OOK") + HAD (synonym="consumed") + ONE (synonym="ace") = METHADONE; definition: "drug" The answer is METHADONE.

Crosophile initially took (consumed) an ace drug (9)

Independent Cryptic #11633 | 3 Down | 2024-01-23 flower

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