What does the cryptic crossword clue "Despairing son overwhelmed by fate (4)" mean?

The definition is "fate". The wordplay uses a container (one word inside another). S (synonym="son") in LOT (synonym="fate") = LOST The answer is LOST.

Despairing son overwhelmed by fate (4)

Independent Cryptic #11654 | 29 Across | 2024-02-16 flower

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