What does the cryptic crossword clue "Doctor with lot there now has to admit defeat (5,2,3,5)" mean?

The definition is "to admit defeat". The wordplay uses an anagram. anagram of WITH + LOT + THERE + NOW = THROWINTHETOWEL; definition: "to admit defeat" The answer is THROWINTHETOWEL.

Doctor with lot there now has to admit defeat (5,2,3,5)

Daily Mail Cryptic #17259 | 1 Down | 2023-12-28 flower

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