What does the cryptic crossword clue "Dominate finest horse (8)" mean?

The definition is "horse". The wordplay uses a charade (building blocks). BEST (synonym="finest") + RIDE (synonym="horse") = BESTRIDE; definition: "Dominate" The answer is BESTRIDE.

Dominate finest horse (8)

Guardian Cryptic #27448 | 4 Down | 2018-03-05 flower

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