What does the cryptic crossword clue "Fellow holding party has upset an iconic female (7)" mean?

The definition is "iconic female". The wordplay uses a reversal. MADON (synonym="MADON") + NA (synonym="NA") = MADONNA; definition: "iconic female" The answer is MADONNA.

Fellow holding party has upset an iconic female (7)

Guardian Cryptic #29102 | 5 Down | 2023-06-21 flower

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