What does the cryptic crossword clue "First of germs caught in hanky you and I lifted, gripping item (5,5)" mean?

This cryptic clue uses wordplay to arrive at the answer. Visit the page for progressive hints — definition, wordplay type, and a full step-by-step explanation.

First of germs caught in hanky you and I lifted, gripping item (5,5)

Guardian Cryptic #29269 | 14 Down | 2024-01-03

Generating...

I haven't cracked this one yet — but the brilliant team at Fifteensquared have:

G[erms] in reverse of SNOTRAG US (you and I? Hmm…)

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