Futile gesture snubbed by crossword setters online (5)

Independent Cryptic #12052 | 7 Down | 2025-05-26
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I haven't cracked this one yet — but the brilliant team at Fifteensquared have:

No[d](=gesture with last letter “snubbed”) + us(=crossword setters) + E(=online, as in E-commerce)

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