What does the cryptic crossword clue "Greek characters Doctor Who companion picked up (4)" mean?

The wordplay uses a homophone (sounds like). Sounds like “Rose” [Tyler], companion of the Doctor when the series was revived in 2005 The answer is RHOS.

Greek characters Doctor Who companion picked up (4)

Guardian Cryptic #29582 | 21 Across | 2025-01-03 flower

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