Guys are going for Nobel from the outset - one's perfect (6)

I haven't cracked this one yet — but the brilliant team at Fifteensquared have:

TE a SES (guys) with the ‘a’ (are – metric measurement of area) replaced by or ‘going for’ N (first letter or ‘outset’ of Nobel  – a reference perhaps to Trump’s desire to be awarded a Nobel Peace Prize)