What does the cryptic crossword clue "Head off from Wyoming in terrible disgrace (8)" mean?

The definition is "disgrace". The wordplay uses an anagram. anagram of YOMING (synonym="YOMING") + IN (synonym="IN") = IGNOMINY; definition: "disgrace" The answer is IGNOMINY.

Head off from Wyoming in terrible disgrace (8)

Guardian Cryptic #27359 | 18 Down | 2017-11-20 flower

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