What does the cryptic crossword clue "Injury largely was responsible for career (6)" mean?

The definition is "career". The wordplay uses a charade (building blocks). HURT (synonym="injury") + LE (synonym="LE") = HURTLE; definition: "career" The answer is HURTLE.

Injury largely was responsible for career (6)

Guardian Cryptic #29294 | 24 Across | 2024-02-01 flower

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