What does the cryptic crossword clue "Instruct a claim must fail, given such evidence (14)" mean?

The definition is "given such evidence". The wordplay uses an anagram. anagram of INSTRUCT + A + CLAIM = CIRCUMSTANTIAL; definition: "given such evidence" The answer is CIRCUMSTANTIAL.

Instruct a claim must fail, given such evidence (14)

Guardian Cryptic #29100 | 27 Across | 2023-06-19 flower

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