What does the cryptic crossword clue "Irritate right joint (6)" mean?

The definition is "Irritate". The wordplay uses a charade (building blocks). R (abbreviation="right") + ANKLE (synonym="joint") = RANKLE; definition: "Irritate" The answer is RANKLE.

Irritate right joint (6)

Daily Mail Cryptic #16499 | 22 Down | 2021-01-27 flower

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