What does the cryptic crossword clue "Joke about weight taken the wrong way — toxic stuff! (5)" mean?

The definition is "toxic stuff". The wordplay uses a reversal. OZ (synonym="ounce") + ONE (synonym="joke, as in ‘Have you heard the one about the Englishman, the Scotsman and the Irishman?’") = OZONE; definition: "— toxic stuff!" The answer is OZONE.

Joke about weight taken the wrong way — toxic stuff! (5)

Times Cryptic #29089 | 24 Down | 2024-12-02 flower

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