Lacking nose Tycho ultimately miserable for nothing (9)

I haven't cracked this one yet — but the brilliant team at Fifteensquared have:

Last letter (ultimately) of [tych] O + DOUR (miserable) + FREE (for nothing = at no cost). “Nose” as in wine-speak = scent. The surface suggests the Renaissance astronomer Tycho Brahe, who lost part of his nose in a duel during his student days and wore a metal prosthesis for the rest of his life.