What does the cryptic crossword clue "Large and small guitar book (4)" mean?

The definition is "book". The wordplay uses a charade (building blocks). L (synonym="large") + UKE (synonym="ukulele; small guitar") = LUKE; definition: "book" The answer is LUKE.

Large and small guitar book (4)

Independent Cryptic #11801 | 24 Across | 2024-08-06 flower

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