What does the cryptic crossword clue "Lead poisoning primarily leads to backache (8)" mean?

The definition is "Lead". The wordplay uses acrostic. P (first_letter="poisoning") + LUMBAGO (synonym="backache") = PLUMBAGO; definition: "Lead" The answer is PLUMBAGO.

Lead poisoning primarily leads to backache (8)

Independent Cryptic #11639 | 1 Down | 2024-01-30 flower

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