Long snake about to eat iguana's head (6)

Independent Cryptic #11310 | 4 Across | 2023-01-11
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I haven't cracked this one yet — but the brilliant team at Fifteensquared have:

ASP (snake) + RE (about = on the subject of), containing (to eat) the first letter (head) of I [guana]. Long, as a verb = aspire = yearn.

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