What does the cryptic crossword clue "Lose example of big road kill (6)" mean?

The definition is "Lose". The wordplay uses a charade (building blocks). MI (synonym="i.e.M1, ‘example of big road’") + SLAY (synonym="‘kill’") = MISLAY; definition: "Lose" The answer is MISLAY.

Lose example of big road kill (6)

Guardian Cryptic #29245 | 6 Across | 2023-12-05 flower

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