Macerate a substance picked after first of apples, most of the time (2,5,2,3)

Guardian Cryptic #29239 | 27 Across | 2023-11-28
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I haven't cracked this one yet — but the brilliant team at Fifteensquared have:

After [ first of ] A (pples), SOFTEN ("macerate") + A + SNOT ("substance picked")

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