What does the cryptic crossword clue "Mad appeals about part of anatomy (5,5)" mean?

The definition is "anatomy". The wordplay uses an anagram. anagram of MAD + APPEALS = ADAMSAPPLE; definition: "anatomy" The answer is ADAMSAPPLE.

Mad appeals about part of anatomy (5,5)

Guardian Cryptic #27556 | 5 Down | 2018-07-09 flower