What does the cryptic crossword clue "Major artery that road from the east crosses (5)" mean?

The definition is "Major artery". The wordplay uses a hidden word. Hidden reversed in "major artery thAT ROAd from the east crosses" The answer is AORTA.

Major artery that road from the east crosses (5)

Times Cryptic #28697 | 23 Across | 2023-09-01 flower

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