What does the cryptic crossword clue "Make mad, awfully enraged or otherwise angered (7)" mean?

The definition is "Make". The wordplay uses an anagram. anagram of ENRAGED ("enraged") [anagram: "otherwise"] = DERANGE; definition: "Make mad," The answer is DERANGE.

Make mad, awfully enraged or otherwise angered (7)

Guardian Cryptic #29214 | 21 Across | 2023-10-30 flower

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