What does the cryptic crossword clue "Makes an enemy of worker and worries deeply (11)" mean?

The definition is "Makes an enemy of". The wordplay uses a charade (building blocks). ANT (synonym="”worker”") + AGONISES (synonym="”worries deeply”") = ANTAGONISES; definition: "Makes an enemy of" The answer is ANTAGONISES.

Makes an enemy of worker and worries deeply (11)

Guardian Cryptic #28874 | 8 Down | 2022-09-28 flower

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