What does the cryptic crossword clue "Mature response is particularly effective, initially (4)" mean?

This cryptic clue uses wordplay to arrive at the answer. Visit the page for progressive hints — definition, wordplay type, and a full step-by-step explanation.

Mature response is particularly effective, initially (4)

Telegraph Prize Cryptic #3189 | 29 Across | 2022-12-04 flower

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