What does the cryptic crossword clue "Musical instruction that unites those twenty instruments, first of all (5)" mean?

This cryptic clue uses wordplay to arrive at the answer. Visit the page for progressive hints — definition, wordplay type, and a full step-by-step explanation.

Musical instruction that unites those twenty instruments, first of all (5)

Telegraph Prize Cryptic #3250 | 6 Down | 2024-02-04 flower

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