No trouble taking 50 away from 16A + (8)

I haven't cracked this one yet — but the brilliant team at Fifteensquared have:

No trouble taking 50 away from 16A + 19 P <l> AIN (=entry at 16A; “taking 50 (=L, in Roman numerals) away” means letter “l” is dropped) + LESS (=minor, i.e. entry at 19, inferior)