What does the cryptic crossword clue "One driven mad by Regan and ilk? (4,4)" mean?

The definition is "One driven". The wordplay uses an anagram. anagram of REGAN (synonym="REGAN") + ILK (synonym="ILK") = KINGLEAR The answer is KINGLEAR.

One driven mad by Regan and ilk? (4,4)

Guardian Cryptic #28970 | 1 Across | 2023-01-18 flower

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