What does the cryptic crossword clue "One turned agonisingly from gang after attempts to get picked up (10)" mean?

The definition is "One turned agonisingly". The wordplay uses a charade (building blocks). THUMBS (synonym="attempts to get picked up [as a hitchhiker]") + CREW (synonym="gang") = THUMBSCREW; definition: "One turned agonisingly" The answer is THUMBSCREW.

One turned agonisingly from gang after attempts to get picked up (10)

Times Cryptic #28625 | 13 Down | 2023-06-09 flower

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