What does the cryptic crossword clue "Possibly an upright secretary accepts one refusal (5)" mean?

This cryptic clue uses wordplay to arrive at the answer. Visit the page for progressive hints — definition, wordplay type, and a full step-by-step explanation.

Possibly an upright secretary accepts one refusal (5)

Daily Mail Cryptic #16411 | 12 Down | 2020-09-25

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