What does the cryptic crossword clue "Run studio cast in moving tragedy (5,10)" mean?

This cryptic clue uses wordplay to arrive at the answer. Visit the page for progressive hints — definition, wordplay type, and a full step-by-step explanation.

Run studio cast in moving tragedy (5,10)

Guardian Cryptic #24606 | 16 Across | 2009-01-26 flower

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