What does the cryptic crossword clue "Seat fan replaced in U.S. city (5,2)" mean?

The definition is "U.S. city". The wordplay uses an anagram. anagram of SEAT + FAN = SANTAFE; definition: "U.S. city" The answer is SANTAFE.

Seat fan replaced in U.S. city (5,2)

Daily Mail Cryptic #17035 | 21 Down | 2023-02-16 flower