What does the cryptic crossword clue "Serious detectives in London departed here (9)" mean?

This cryptic clue uses wordplay to arrive at the answer. Visit the page for progressive hints — definition, wordplay type, and a full step-by-step explanation.

Serious detectives in London departed here (9)

Daily Mail Cryptic #16836 | 14 Across | 2022-05-13

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