What does the cryptic crossword clue "Skin disease: woman’s source of annoyance mostly (6)" mean?

This cryptic clue uses wordplay to arrive at the answer. Visit the page for progressive hints — definition, wordplay type, and a full step-by-step explanation.

Skin disease: woman’s source of annoyance mostly (6)

Independent Cryptic #11624 | 28 Across | 2024-01-12 flower

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