What does the cryptic crossword clue "Spirit of destiny overlooking one part of family (5)" mean?

The definition is "family". The wordplay uses a charade (building blocks). GEN (synonym="GEN") + US (synonym="from Roman mythology, the guardian spirit for a person, nation, or place") = GENUS; definition: "part of family" The answer is GENUS.

Spirit of destiny overlooking one part of family (5)

Independent Cryptic #11852 | 10 Across | 2024-10-04 flower

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