What does the cryptic crossword clue "Spirits after cold beer befuddled the brain (8)" mean?

The definition is "brain". The wordplay uses an anagram. anagram of BEER (synonym="befuddled") + RUM (synonym="example of spirits") + C (synonym="cold") = CEREBRUM The answer is CEREBRUM.

Spirits after cold beer befuddled the brain (8)

Independent Cryptic #11618 | 29 Across | 2024-01-05 flower

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