What does the cryptic crossword clue "Spouse in extremis — case for narcotic? (8)" mean?

The definition is "narcotic". The wordplay uses charade, parts. SE (middle of "Spouse") + DATIVE (synonym of "- case") [outer letters: "in extremis"]; definition: "narcotic?" The answer is SEDATIVE.

Spouse in extremis — case for narcotic? (8)

Times Cryptic #28748 | 1 Across | 2023-10-31 flower

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