What does the cryptic crossword clue "Supremely evil influence in Chartist reforms (10)" mean?

The definition is "Supremely evil influence". The wordplay uses an anagram. anagram of IN + CHARTIST = ANTICHRIST; definition: "Supremely evil influence" The answer is ANTICHRIST.

Supremely evil influence in Chartist reforms (10)

Independent Cryptic #1768 | 15 Down | 2024-01-14 flower

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Also seen in

Telegraph #29341 (2020-04-18) Guardian Cryptic #26988 (2016-09-13)