Took the lead from sanctimonious individual left holding drug (9)

Guardian Cryptic #29190 | 24 Across | 2023-10-02
Generating...

I haven't cracked this one yet — but the brilliant team at Fifteensquared have:

PI (short for pious, "sanctimonious") + ONE="individual" + RED (as in socialist, "left"); around E (ecstasy, "drug")

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