What does the cryptic crossword clue "Trouble going from Syria with initially unnoticed drug supply (7)" mean?

The definition is "Trouble". The wordplay uses an anagram. anagram of SYRIA (synonym="supply [derived from supple]") + UD (synonym="first letters of [initially] U NNOTICED and D RUG") = DYSURIA The answer is DYSURIA.

Trouble going from Syria with initially unnoticed drug supply (7)

Independent Cryptic #11887 | 24 Across | 2024-11-14 flower

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