What does the cryptic crossword clue "Ultimately harmful combo, big effects if activated (5,4)" mean?

This cryptic clue uses wordplay to arrive at the answer. Visit the page for progressive hints — definition, wordplay type, and a full step-by-step explanation.

Ultimately harmful combo, big effects if activated (5,4)

Guardian Cryptic #29958 | 13 Down | 2026-03-19 flower

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