What does the cryptic crossword clue "Unable to meet the challenge in bed, turn over one time (3,2,2,2)" mean?

The wordplay uses a charade (building blocks). NOT (synonym="NOT") + UP (synonym="in bed") + T (synonym="turn – as in PTO? I can’t find it otherwise") + O (synonym="over") + I (synonym="one") + T (synonym="turn – as in PTO? I can’t find it otherwise") = NOTUPTOIT The answer is NOTUPTOIT.

Unable to meet the challenge in bed, turn over one time (3,2,2,2)

Guardian Cryptic #28988 | 11 Across | 2023-02-08 flower

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