What does the cryptic crossword clue "Uptight, nursing temperature, oxygen off the scale (6)" mean?

This cryptic clue uses wordplay to arrive at the answer. Visit the page for progressive hints — definition, wordplay type, and a full step-by-step explanation.

Uptight, nursing temperature, oxygen off the scale (6)

Times Cryptic #29067 | 28 Across | 2024-11-06

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I haven't cracked this one yet — but the brilliant team at Times for the Times have:

uptight = ANAL, insert T, O, for temperature, oxygen.

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