What may poison police struggling without leadership (5)

Independent Cryptic #11881 | 24 Down | 2024-11-07
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I haven't cracked this one yet — but the brilliant team at Fifteensquared have:

Anagram (struggling) of [p] OLICE without the first letter (leadership). Abbreviation for Escherichia coli , a bacterium that can cause serious food poisoning.

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